منابع مشابه
Fly Memory: A Mushroom Body Story in Parts
Recent studies on the compartmentalization of fly mushroom bodies show that learning and memory in Drosophila are not as simple as might be expected for an organism with such a tiny brain.
متن کاملMemory-Relevant Mushroom Body Output Synapses Are Cholinergic
Memories are stored in the fan-out fan-in neural architectures of the mammalian cerebellum and hippocampus and the insect mushroom bodies. However, whereas key plasticity occurs at glutamatergic synapses in mammals, the neurochemistry of the memory-storing mushroom body Kenyon cell output synapses is unknown. Here we demonstrate a role for acetylcholine (ACh) in Drosophila. Kenyon cells express...
متن کاملLocalization of long-term memory within the Drosophila mushroom body.
The mushroom bodies, substructures of the Drosophila brain, are involved in olfactory learning and short-term memory, but their role in long-term memory is unknown. Here we show that the alpha-lobes-absent (ala) mutant lacks either the two vertical lobes of the mushroom body or two of the three median lobes which contain branches of vertical lobe neurons. This unique phenotype allows analysis o...
متن کاملAdditive Expression of Consolidated Memory through Drosophila Mushroom Body Subsets
Associative olfactory memory in Drosophila has two components called labile anesthesia-sensitive memory and consolidated anesthesia-resistant memory (ARM). Mushroom body (MB) is a brain region critical for the olfactory memory and comprised of 2000 neurons that can be classified into αβ, α'β', and γ neurons. Previously we demonstrated that two parallel pathways mediated ARM consolidation: the s...
متن کاملThe mushroom body
On the contrary. Wrangham's book comes at a crucial time. Driven by technical accomplishments, the past years have seen huge interest in identifying genes whose adaptive changes underlie human evolution. This enterprise may have, to some extent, shifted the focus away from environmental and in particular cultural drivers of human evolution. Cooking is a key cultural practice of humans and it is...
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ژورنال
عنوان ژورنال: Current Biology
سال: 2009
ISSN: 0960-9822
DOI: 10.1016/j.cub.2009.07.064